Chen lab publications

Selected Publications

Evolution and genomic diversity of periodontal pathogens

  1. Kittichotirat W, Bumgarner RE, Chen C. Evolutionary Divergence of Aggregatibacter actinomycetemcomitans. Journal of Dental Research. 2016; 95(1):94-101. PubMed [journal] PMID: 26420795, PMCID: PMC4700661
  2. Tang-Siegel G, Bumgarner R, Ruiz T, Kittichotirat W, Chen W, Chen C. Human Serum-Specific Activation of Alternative Sigma Factors, the Stress Responders in Aggregatibacter actinomycetemcomitans. PloS one. 2016; 11(8):e0160018. PubMed [journal] PMID: 27490177, PMCID: PMC4973924
  3. Sun R, Kittichotirat W, Wang J, Jan M, Chen W, Asikainen S, Bumgarner R, Chen C. Genomic Stability of Aggregatibacter actinomycetemcomitans during Persistent Oral Infection in Human. PloS one. 2013; 8(6):e66472. PubMed [journal] PMID: 23824402, PMCID: PMC3688926
  4. Huang Y, Kittichotirat W, Mayer MP, Hall R, Bumgarner R, Chen C. Comparative genomic hybridization and transcriptome analysis with a pan-genome microarray reveal distinctions between JP2 and non-JP2 genotypes of Aggregatibacter actinomycetemcomitans. Molecular oral microbiology. 2013; 28(1):1-17. NIHMSID: NIHMS405344 PubMed [journal] PMID: 23194436, PMCID: PMC3543495

Oral microbiota of periodontal health and disease

  1. Chen C, Feng P, Slots J. Herpesvirus-bacteria synergistic interaction in periodontitis. Periodontol 2000. 2020;82(1):42-64. doi:10.1111/prd.12311.
  2. Chen C, Hemme C, Beleno J, Shi ZJ, Ning D, Qin Y, Tu Q, Jorgensen M, He Z, Wu L, Zhou J. Oral microbiota of periodontal health and disease and their changes after nonsurgical periodontal therapy. The ISME journal. 2018; 12(5):1210-1224. PubMed [journal] PMID: 29339824, PMCID: PMC5932080
  3. Manrique P, Freire MO, Chen C, Zadeh HH, Young M, Suci P. Perturbation of the indigenous rat oral microbiome by ciprofloxacin dosing. Molecular Oral microbiology. 2013; 28(5):404-14. NIHMSID: NIHMS494115 PubMed [journal] PMID: 23844936, PMCID: PMC3767763
  4. Laksmana T, Kittichotirat W, Huang Y, Chen W, Jorgensen M, Bumgarner R, Chen C. Metagenomic analysis of subgingival microbiota following non-surgical periodontal therapy: a pilot study. The open dentistry journal. 2012; 6:255-61. PubMed [journal] PMID: 23341849, PMCID: PMC3547359

Pathogenesis of A. actinomycetemcomitans

  1. Sha Q, Chen C. Effect of different Aggregatibacter actinomycetemcomitans strains on dual-species biofilms formed with Porphyromonas gingivalis or Dialister pneumosintes. Eur J Oral Sci. 2020;128(2):136-144. doi:10.1111/eos.12682
  2. Tjokro NO, Kittichotirat W, Torittu A, Ihalin R, Bumgarner RE, Chen C. Transcriptomic Analysis of Aggregatibacter actinomycetemcomitans core and accessory genes in different growth conditions. Pathogens. 2019;8(4):282. doi:10.3390/pathogens8040282
  3. Yang YA, Cheng YA, Chen C. Genomic integration and expression of the Aggregatibacter actinomycetemcomitans catalase gene in Aggregatibacter aphrophilus. Archives of Oral Biology. 2018; 86:116-122. NIHMSID: NIHMS926028 PubMed [journal] PMID: 29223024, PMCID: PMC5792192
  4. Mahabady S, Tjokro N, Aharonian S, Zadeh HH, Chen C, Allayee H, Sedghizadeh PP. The in vivo T helper type 17 and regulatory T cell immune responses to Aggregatibacter actinomycetemcomitans. Molecular oral microbiology. 2017; 32(6):490-499. NIHMSID: NIHMS945637 PubMed [journal] PMID: 28544588, PMCID: PMC5842142
  5. Freire MO, Devaraj A, Young A, Navarro JB, Downey JS, Chen C, Bakaletz LO, Zadeh HH, Goodman SD. A bacterial-biofilm-induced oral osteolytic infection can be successfully treated by immuno-targeting an extracellular nucleoid-associated protein. Molecular oral microbiology. 2017; 32(1):74-88. NIHMSID: NIHMS764780 PubMed [journal] PMID: 26931773, PMCID: PMC5010536
  6. Karched M, Ihalin R, Eneslätt K, Zhong D, Oscarsson J, Wai SN, Chen C, Asikainen SE. Vesicle-independent extracellular release of a proinflammatory outer membrane lipoprotein in free-soluble form. BMC microbiology. 2008; 8:18. PubMed [journal] PMID: 18226201, PMCID: PMC2257964

Clinical and microbial diagnosis of periodontal health and disease

  1. Wisdom EC, Zhou Y, Chen C, Tamerler C, Snead ML. Mitigation of peri-implantitis by rational design of bifunctional peptides with antimicrobial properties. ACS Biomater Sci Eng. 2020;6(5):2682-2695. doi:10.1021/acsbiomaterials.9b01213
  2. Wisdom C, Chen C, Yuca E, Zhou Y, Tamerler C, Snead ML. Repeatedly applied peptide film kills bacteria on dental implant. JOM, 2019, Apr;71(4):1271-1280.
  3. Moore C, Bai Y, Hariri A, Sanchez JB, Lin C-Y, Koka S, Sedghizadeh P, Chen C, and Jokerst JV: Photoacoustic imaging for monitoring periodontal health: A first human study. Photoacoustics In Press. 2018.
  4. Doan N, Contreras A, Flynn J, Slots J, Chen C. Molecular identification of Dialister pneumosintes in subgingival plaque of humans. Journal of clinical microbiology. 2000; 38(8):3043-7. PubMed [journal] PMID: 10921975, PMCID: PMC87182
  5. Contreras A, Doan N, Chen C, Rusitanonta T, Flynn MJ, Slots J. Importance of Dialister pneumosintes in human periodontitis. Oral microbiology and immunology. 2000; 15(4):269-72. PubMed [journal] PMID: 11154414
  6. Chen C, Slots J. Microbiological tests for Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. Periodontology 2000. 1999; 20:53-64. PubMed [journal] PMID: 10522222
  7. Ashimoto A, Chen C, Bakker I, Slots J. Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions. Oral microbiology and immunology. 1996; 11(4):266-73. PubMed [journal] PMID: 9002880

 

Complete List of Published Work in MyBibliography