RECENT SIGNIFICANT PUBLICATIONS
- Zhao J, Tian M, Zhang S, Delfarah A, Gao R, Rao Y, Savas AC, Lu A, Bubb L, Lei X, Moshirian R, Zhu W, Peng C, Jiang T, Chen L, Graham NA, Feng P. Deamidation shunts RelA from mediating inflammation to aerobic glycolysis. Cell Metab. 2020 May 5;31(5):937-955.e7. doi: 10.1016/j.cmet.2020.04.006. Epub 2020 Apr 22.PMID: 32325032
- Li J, Zhao J, Xu S, Zhang S, Zhang J, Xiao J, Gao R, Tian M, Zeng Y, Lee K, Tarakanova V, Lan K, Feng H, Feng P. Antiviral activity of a purine synthesis enzyme reveals a key role of deamidation in regulating protein nuclear import. Sci Adv. 2019 Oct 9;5(10):eaaw7373. doi: 10.1126/sciadv.aaw7373. eCollection 2019 Oct.PMID: 31633017
- He S, Zhao J, Song S, He X, Minassian A, Zhou Y, Zhang J, Brulois K, Wang Y, Cabo J, Zandi E, Liang C, Jung JU, Zhang X, Feng P. Viral pseudo-enzymes activate RIG-I via deamidation to evade cytokine production. Mol Cell. 2015 Apr 2;58(1):134-46. doi: 10.1016/j.molcel.2015.01.036. Epub 2015 Mar 5. PubMed PMID: 25752576; PubMed Central PMCID: PMC4385502. Preview section by Daniel Kolakofsky and Dominique Garcin.
- Zhang J, Feng H, Zhao J, Feldman ER, Chen SY, Yuan WM, Huang C, Akbari O, Tibbetts SA, and Feng P. IkB e kinase is an NFATc1 kinase that inhibits T cell immune responses. Cell Reports 2016 Jul 12;16(2):405-18. doi: 10.1016/j.celrep.2016.05.083.
- Zhao J, Zeng Y, Xu SM, Chen J, Shen G, Yu C, Peng J, Knipe DM, Yuan WM, Xu WQ, Zhang C, Xia Z, and Feng P. A viral deamidase targets RIG-I to block RNA-induced activation. Cell Host & Microbe. 2016 Nov 16. pii: S1931-3128(16)30437-1. doi: 10.1016/j.chom.2016.10.011. Preview section by Dominique Garcin.
- Zhang J, Zhao J, Li J, Xu S, He S, Zeng Y, Xie L, Xie N, Liu T, Lee K, Seo G-J, Chen L, Stabell, A.C, Xia Z, Sawyer S.L, Jung JU, Huang C, and Feng P. Species-specific deamidation of cGAS facilitates herpes simplex virus 1 lytic replication. Cell Host & Microbe. 2018 Aug 8;24(2):234-248.e5. doi: 10.1016/j.chom.2018.07.004. See highlight in Science Signaling.
- Qin C, Feng S, Feng P. STeerING PI4P for innate immune activation. Immunity. 2023. 14;56(3):463-465. PMID: 36921569
- Qin C, Rao Y, Yuan H, Wang T, Zhao J, Espinosa B, Liu Y, Zhang S, Savas AC, Liu Q, Zarinfar M, Rice S, Henley J, Comai L, Graham NA, Chen C, Zhang C and Feng P. SARS-CoV-2 Couples Evasion of Inflammatory Response to Activated Nucleotide Synthesis. PNAS. 2022. 119(26):e2122897119. PMID: 35700355